UCT Repository Prague BACHELOR THESIS

Acylace toluenu 2-chlorobenzoylchloridem a 2,4-dichlorobenzoylchloridem na zeolitových katalyzátorech

Toluene acylation with 2-chlorobenzoylchloride and 2,4-dichlorobenzoylchloride over the zeolite catalysts

Bc. Denisa Dvořáková

UCT Repository Prague BACHELOR THESIS

Acylace toluenu 2-chlorobenzoylchloridem a 2,4-dichlorobenzoylchloridem na zeolitových katalyzátorech

Toluene acylation with 2-chlorobenzoylchloride and 2,4-dichlorobenzoylchloride over the zeolite catalysts

Bc. Denisa Dvořáková

Tato práce se zabývala studiem acylace toluenu 2-chlorobenzoylchloridem a 2,4-dichlorobenzoylchloridem na různých strukturách zeolitů. Cílem práce bylo zjistit, na kterém katalyzátoru bude dosaţeno nejvyšší konverze toluenu a nejyvšší selektivity acylovaného produktu. Při acylaci toluenu vznikaly tři produkty, které byly určeny podle spekter hmotnostní spektrometrie. Při acylaci toluenu 2-chlorobenzoylchloridem byly vznikající produkty určeny jako ethyl-2-chlorobenzoát (1), 2-chloro-2´-methylbenzofenon/ 2-chloro-4´-methylbenzofenon (2) a formylfenyl-2-chlorobenzoát (3). Nejvyšší konverze toluenu bylo dosaţeno pro obě acylační činidla na zeolitech USY a BEA, maximálně však 40,0%. Selektivita na produkt (1) byla skoro nulová. Acylační reakce byly nejvíce selektivní na produkt (3). Selektivita na acylovan…

This work deals with studying of the acylation of toluene with 2-chlorobenzoylchloride and 2,4-dichlorobenzoylchloride over zeolite catalysts. The aim was to find, which zeolite catalyst exhibits the highest conversion of toluene and the highest selectivity to acylation product. The acylation of toluene provides three products, which were determined by mass spectroscopy. The acylation of toluene with 2-chlorobenzoylchloride provides ethyl-2-chlorobenzoate (1), 2-chloro-2'-methylbenzophenone / 2-chloro-4'-methylbenzophenone (2) and formylphenyl-2-chlorobenzoate (3). The highest selectivity to product (3) was observed. The maximum selectivity to acylation products reached about 40 %. The acylation of toluene with 2,4-dichlorobenzyolchloride provides ethyl-2,4-dichlorobenzoate (1), 2,4-dichloro-2 '-methyl…

Advisor: doc. Ing. Jiří Trejbal, Ph.D.
prof. Ing. Jiří Čejka, DrSc.
Thesis type: Bachelor thesis
Institution: University of Chemistry and Technology, Prague
Faculty: Faculty of Chemical Technology
Department: Department of Organic Technology
Study programme: Drug Synthesis and Production
Specialization / field: Synthesis and Production of Drugs
MŠMT code: 2801R017
Language: Czech
Resource accessibility: The printed version of the thesis is available at the department where the thesis was produced. Defence protocol and reviews are available at UCT Prague archive.
Access rights: open access
SIS ID: 11184
Date available: Mar 4, 2014
Date modified: Mar 4, 2014
Date defended: Jun 29, 2011DEFENDED

Acylace toluenu 2-chlorobenzoylchloridem a 2,4-dichlorobenzoylchloridem na zeolitových katalyzátorech

Toluene acylation with 2-chlorobenzoylchloride and 2,4-dichlorobenzoylchloride over the zeolite catalysts

Acylace toluenu 2-chlorobenzoylchloridem a 2,4-dichlorobenzoylchloridem na zeolitových katalyzátorech

Toluene acylation with 2-chlorobenzoylchloride and 2,4-dichlorobenzoylchloride over the zeolite catalysts

ANOTACE

ANNOTATION